The neuronal growth and regeneration associated Cntn1 (F3/F11/Contactin) gene is duplicated in fish: expression during development and retinal axon regeneration
Dateien
Datum
Autor:innen
Herausgeber:innen
ISSN der Zeitschrift
Electronic ISSN
ISBN
Bibliografische Daten
Verlag
Schriftenreihe
Auflagebezeichnung
URI (zitierfähiger Link)
DOI (zitierfähiger Link)
Internationale Patentnummer
Link zur Lizenz
Angaben zur Forschungsförderung
Projekt
Open Access-Veröffentlichung
Sammlungen
Core Facility der Universität Konstanz
Titel in einer weiteren Sprache
Publikationstyp
Publikationsstatus
Erschienen in
Zusammenfassung
The Cntn1 (Contactin/F3/F11) cell adhesion molecule is involved in axon growth and guidance, fasciculation, synapse formation, and myelination in birds and mammals. We identified Cntn1 genes in goldfish, zebrafish, and fugu, and provide evidence for a fish-specific duplication leading to Cntn1a and Cntn1b. Our analyses suggest a subfunctionalization for the Cntn1 paralogs in zebrafish compared to other vertebrates which have a single Cntn1 gene. Similar to Cntn1a, Cntn1b transcripts are found in subsets of sensory and motor neurons. However, Cntn1b is detected later and more restricted than Cntn1a. This spatio-temporal expression pattern of the two zebrafish Cntn1 paralogs suggests functions related to those of mammalian Cntn1. In adult goldfish, Cntn1b is expressed in oligodendrocytes and is upregulated in retinal ganglion cells after optic nerve transection, which is consistent with an additional role during regeneration
The neuronal growth and regeneration associated Cntn1 (F3/F11/Contactin) gene is duplicated in fish: expression during development and retinal axon regeneration
Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
Schlagwörter
Konferenz
Rezension
Zitieren
ISO 690
HAENISCH, Christina, Heike DIEKMANN, Michael KLINGER, Gianfranco GENNARINI, John Y. KUWADA, Claudia STÃœRMER, 2005. The neuronal growth and regeneration associated Cntn1 (F3/F11/Contactin) gene is duplicated in fish: expression during development and retinal axon regeneration. In: Molecular and Cellular Neuroscience. 2005, 28(2), pp. 361-374. ISSN 1044-7431. Available under: doi: 10.1016/j.mcn.2004.04.013BibTex
@article{Haenisch2005-02neuro-16902, year={2005}, doi={10.1016/j.mcn.2004.04.013}, title={The neuronal growth and regeneration associated Cntn1 (F3/F11/Contactin) gene is duplicated in fish: expression during development and retinal axon regeneration}, number={2}, volume={28}, issn={1044-7431}, journal={Molecular and Cellular Neuroscience}, pages={361--374}, author={Haenisch, Christina and Diekmann, Heike and Klinger, Michael and Gennarini, Gianfranco and Kuwada, John Y. and Stürmer, Claudia} }
RDF
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:void="http://rdfs.org/ns/void#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/16902"> <dc:creator>Klinger, Michael</dc:creator> <foaf:homepage rdf:resource="http://localhost:8080/"/> <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/> <dc:contributor>Stürmer, Claudia</dc:contributor> <dc:contributor>Klinger, Michael</dc:contributor> <dc:contributor>Gennarini, Gianfranco</dc:contributor> <dc:creator>Stürmer, Claudia</dc:creator> <dc:contributor>Kuwada, John Y.</dc:contributor> <dc:language>eng</dc:language> <dc:rights>terms-of-use</dc:rights> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2012-01-12T13:16:09Z</dcterms:available> <dc:creator>Gennarini, Gianfranco</dc:creator> <dc:creator>Diekmann, Heike</dc:creator> <dcterms:title>The neuronal growth and regeneration associated Cntn1 (F3/F11/Contactin) gene is duplicated in fish: expression during development and retinal axon regeneration</dcterms:title> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/16902"/> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2012-01-12T13:16:09Z</dc:date> <dc:contributor>Diekmann, Heike</dc:contributor> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/16902/2/Haenisch_169026.pdf"/> <dcterms:issued>2005-02</dcterms:issued> <dcterms:abstract xml:lang="eng">The Cntn1 (Contactin/F3/F11) cell adhesion molecule is involved in axon growth and guidance, fasciculation, synapse formation, and myelination in birds and mammals. We identified Cntn1 genes in goldfish, zebrafish, and fugu, and provide evidence for a fish-specific duplication leading to Cntn1a and Cntn1b. Our analyses suggest a subfunctionalization for the Cntn1 paralogs in zebrafish compared to other vertebrates which have a single Cntn1 gene. Similar to Cntn1a, Cntn1b transcripts are found in subsets of sensory and motor neurons. However, Cntn1b is detected later and more restricted than Cntn1a. This spatio-temporal expression pattern of the two zebrafish Cntn1 paralogs suggests functions related to those of mammalian Cntn1. In adult goldfish, Cntn1b is expressed in oligodendrocytes and is upregulated in retinal ganglion cells after optic nerve transection, which is consistent with an additional role during regeneration<br />The neuronal growth and regeneration associated Cntn1 (F3/F11/Contactin) gene is duplicated in fish: expression during development and retinal axon regeneration</dcterms:abstract> <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/16902/2/Haenisch_169026.pdf"/> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/> <dc:creator>Kuwada, John Y.</dc:creator> <dcterms:bibliographicCitation>Publ. in: Molecular and Cellular Neuroscience ; 28 (2005), 2. - S. 361-374</dcterms:bibliographicCitation> <dc:contributor>Haenisch, Christina</dc:contributor> <dc:creator>Haenisch, Christina</dc:creator> </rdf:Description> </rdf:RDF>