Polyetheretherketone implant surface functionalization technologies and the need for a transparent quality evaluation system

Lade...
Vorschaubild
Dateien
Schaffarczyk_2-1u4yysh6dcx6j7.pdf
Schaffarczyk_2-1u4yysh6dcx6j7.pdfGröße: 1.1 MBDownloads: 151
Datum
2021
Autor:innen
Herausgeber:innen
Kontakt
ISSN der Zeitschrift
Electronic ISSN
ISBN
Bibliografische Daten
Verlag
Schriftenreihe
Auflagebezeichnung
DOI (zitierfähiger Link)
ArXiv-ID
Internationale Patentnummer
Angaben zur Forschungsförderung
Projekt
Open Access-Veröffentlichung
Open Access Hybrid
Sammlungen
Core Facility der Universität Konstanz
Gesperrt bis
Titel in einer weiteren Sprache
Forschungsvorhaben
Organisationseinheiten
Zeitschriftenheft
Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published
Erschienen in
Polymer International. Wiley. 2021, 70(8), pp. 1002-1015. ISSN 0959-8103. eISSN 1097-0126. Available under: doi: 10.1002/pi.6162
Zusammenfassung

For bone implants, osseointegration resulting in a good and fast bone–implant contact is of primary importance to secure a proper implant function and to avoid implant loosening or inflammation resulting in necessary revision surgeries causing pain to the patients and immense costs. In particular, polyetheretherketone (PEEK) is a promising implant material due to the close mechanical properties to bone, but it is entirely bio‐inert, hindering osseointegration and making surface functionalization necessary. Many different surface functionalization technologies have been reported of both physical and chemical nature. The same is true for the other prominent implant materials titanium and ceramics. Although they already have inherently better osseointegration than PEEK, they are much harder and stiffer than bone and brittle in the case of ceramics. Surface functionalization, which can be subdivided into surface coating and material modification, needs to be judged from a quality and safety viewpoint. However, a literature research resulted in the realization that no quality standard yet exists for implant surface functionalizations. This makes it difficult to near impossible to compare the safety and performance of different surface‐functionalized bone implants, clearly showing the need to establish a transparent quality evaluation system for bone implants. This perspective article gives the state of the art and then develops a quality evaluation system based on six main categories as important benchmarks for the quality of surface‐functionalized bone implant materials. A simple catalog of questions can be answered, and from the resulting scores the Safety and Performance Evidence Level (SPEL) representing the safety and quality of a given implant can be calculated as a percentage. This simple SPEL system allows an easy and transparent judgment and comparison of bone implants, ensuring the easy identification of safe and well‐performing high‐quality bone implants in the future.

Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
540 Chemie
Schlagwörter
Konferenz
Rezension
undefined / . - undefined, undefined
Zitieren
ISO 690SCHAFFARCZYK, Dietmar, Jennifer KNAUS, Gunther PEETERS, Dieter SCHOLL, Andreas SCHWITALLA, Christoph KOSLOWSKI, Helmut CÖLFEN, 2021. Polyetheretherketone implant surface functionalization technologies and the need for a transparent quality evaluation system. In: Polymer International. Wiley. 2021, 70(8), pp. 1002-1015. ISSN 0959-8103. eISSN 1097-0126. Available under: doi: 10.1002/pi.6162
BibTex
@article{Schaffarczyk2021-08Polye-52274,
  year={2021},
  doi={10.1002/pi.6162},
  title={Polyetheretherketone implant surface functionalization technologies and the need for a transparent quality evaluation system},
  number={8},
  volume={70},
  issn={0959-8103},
  journal={Polymer International},
  pages={1002--1015},
  author={Schaffarczyk, Dietmar and Knaus, Jennifer and Peeters, Gunther and Scholl, Dieter and Schwitalla, Andreas and Koslowski, Christoph and Cölfen, Helmut}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/52274">
    <dcterms:title>Polyetheretherketone implant surface functionalization technologies and the need for a transparent quality evaluation system</dcterms:title>
    <dc:creator>Cölfen, Helmut</dc:creator>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/29"/>
    <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/52274"/>
    <dc:contributor>Knaus, Jennifer</dc:contributor>
    <dc:contributor>Koslowski, Christoph</dc:contributor>
    <dcterms:rights rdf:resource="http://creativecommons.org/licenses/by/4.0/"/>
    <dc:contributor>Scholl, Dieter</dc:contributor>
    <dc:language>eng</dc:language>
    <dc:contributor>Schwitalla, Andreas</dc:contributor>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/52274/1/Schaffarczyk_2-1u4yysh6dcx6j7.pdf"/>
    <dc:creator>Scholl, Dieter</dc:creator>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/29"/>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:creator>Knaus, Jennifer</dc:creator>
    <dc:contributor>Cölfen, Helmut</dc:contributor>
    <dcterms:issued>2021-08</dcterms:issued>
    <dc:contributor>Schaffarczyk, Dietmar</dc:contributor>
    <dc:creator>Schaffarczyk, Dietmar</dc:creator>
    <dcterms:abstract xml:lang="eng">For bone implants, osseointegration resulting in a good and fast bone–implant contact is of primary importance to secure a proper implant function and to avoid implant loosening or inflammation resulting in necessary revision surgeries causing pain to the patients and immense costs. In particular, polyetheretherketone (PEEK) is a promising implant material due to the close mechanical properties to bone, but it is entirely bio‐inert, hindering osseointegration and making surface functionalization necessary. Many different surface functionalization technologies have been reported of both physical and chemical nature. The same is true for the other prominent implant materials titanium and ceramics. Although they already have inherently better osseointegration than PEEK, they are much harder and stiffer than bone and brittle in the case of ceramics. Surface functionalization, which can be subdivided into surface coating and material modification, needs to be judged from a quality and safety viewpoint. However, a literature research resulted in the realization that no quality standard yet exists for implant surface functionalizations. This makes it difficult to near impossible to compare the safety and performance of different surface‐functionalized bone implants, clearly showing the need to establish a transparent quality evaluation system for bone implants. This perspective article gives the state of the art and then develops a quality evaluation system based on six main categories as important benchmarks for the quality of surface‐functionalized bone implant materials. A simple catalog of questions can be answered, and from the resulting scores the Safety and Performance Evidence Level (SPEL) representing the safety and quality of a given implant can be calculated as a percentage. This simple SPEL system allows an easy and transparent judgment and comparison of bone implants, ensuring the easy identification of safe and well‐performing high‐quality bone implants in the future.</dcterms:abstract>
    <dc:creator>Schwitalla, Andreas</dc:creator>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2021-01-04T14:51:19Z</dc:date>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2021-01-04T14:51:19Z</dcterms:available>
    <dc:creator>Peeters, Gunther</dc:creator>
    <dc:rights>Attribution 4.0 International</dc:rights>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/52274/1/Schaffarczyk_2-1u4yysh6dcx6j7.pdf"/>
    <dc:contributor>Peeters, Gunther</dc:contributor>
    <dc:creator>Koslowski, Christoph</dc:creator>
  </rdf:Description>
</rdf:RDF>
Interner Vermerk
xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter
Kontakt
URL der Originalveröffentl.
Prüfdatum der URL
Prüfungsdatum der Dissertation
Finanzierungsart
Kommentar zur Publikation
Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
Begutachtet
Ja
Diese Publikation teilen