Toward Good In Vitro Reporting Standards

Hartung, Thomas; De Vries, Rob; Hoffmann, Sebastian; Hogberg, Helena T.; Smirnova, Lena; Tsaioun, Katya; Whaley, Paul; Leist, Marcel

Toward Good In Vitro Reporting Standards

Dateien

Hartung_2-dtknemkfo4ux2.pdfGröße: 1.35 MBDownloads: 376

Datum

2019

Autor:innen

Hartung, Thomas

De Vries, Rob

Hoffmann, Sebastian

Hogberg, Helena T.

Smirnova, Lena

Tsaioun, Katya

Whaley, Paul

Leist, Marcel

Open Access-Veröffentlichung

Open Access Gold

Sammlungen

Biologie

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

Alternatives to Animal Experimentation : ALTEX. 2019, 36(1), pp. 3-17. ISSN 1868-596X. eISSN 1868-8551. Available under: doi: 10.14573/altex.1812191

Zusammenfassung

A good experiment reported badly is worthless. Meaningful contributions to the body of science are made by sharing the full methodology and results so that they can be evaluated and reproduced by peers. Erroneous and incomplete reporting does not do justice to the resources spent on conducting the experiment and the time peers spend reading the article. In theory peer-review should ensure adequate reporting - in practice it does not. Many areas have developed reporting standards and checklists to support the adequate reporting of scientific efforts, but in vitro research still has no generally accepted criteria. It is characterized by a "Wild West" or "anything goes" attitude. Such a culture may undermine trust in the reproducibility of animal-free methods, and thus parallel the "reproducibility crisis" discussed for other life science fields. The increasing data retrieval needs of computational approaches (in extreme as "big data" and artificial intelligence) makes reporting quality even more important so that the scientific community can take full advantage of the results. The first priority of reporting standards is to ensure the completeness and transparency of information provided (data focus). The second tier is a quality of data display that makes information digestible and easy to grasp, compare and further analyze (information focus). This article summarizes a series of initiatives geared towards improving the quality of in vitro work and its reporting. This shall ultimately lead to Good In Vitro Reporting Standards (GIVReSt).

Fachgebiet (DDC)

570 Biowissenschaften, Biologie

Zitieren

ISO 690

HARTUNG, Thomas, Rob DE VRIES, Sebastian HOFFMANN, Helena T. HOGBERG, Lena SMIRNOVA, Katya TSAIOUN, Paul WHALEY, Marcel LEIST, 2019. Toward Good In Vitro Reporting Standards. In: Alternatives to Animal Experimentation : ALTEX. 2019, 36(1), pp. 3-17. ISSN 1868-596X. eISSN 1868-8551. Available under: doi: 10.14573/altex.1812191

BibTex

@article{Hartung2019Towar-44642,
  year={2019},
  doi={10.14573/altex.1812191},
  title={Toward Good In Vitro Reporting Standards},
  number={1},
  volume={36},
  issn={1868-596X},
  journal={Alternatives to Animal Experimentation : ALTEX},
  pages={3--17},
  author={Hartung, Thomas and De Vries, Rob and Hoffmann, Sebastian and Hogberg, Helena T. and Smirnova, Lena and Tsaioun, Katya and Whaley, Paul and Leist, Marcel}
}

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Universitätsbibliographie

Ja

Begutachtet

Ja