Objective assessment of motor fatigue in multiple sclerosis : the Fatigue index Kliniken Schmieder (FKS)

Sehle, Aida; Vieten, Manfred; Sailer, Simon; Mündermann, Annegret; Dettmers, Christian

Objective assessment of motor fatigue in multiple sclerosis : the Fatigue index Kliniken Schmieder (FKS)

Dateien

Sehle_284152.pdfGröße: 804.45 KBDownloads: 979

Datum

2014

Autor:innen

Sailer, Simon

Open Access-Veröffentlichung

Open Access Green

Sammlungen

Sportwissenschaft
Psychologie

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

Journal of Neurology. 2014, 261(9), pp. 1752-1762. ISSN 0340-5354. eISSN 1432-1459. Available under: doi: 10.1007/s00415-014-7415-7

Zusammenfassung

Fatigue is a common and frequently disabling symptom of multiple sclerosis (MS). The aim of this study was to develop the Fatigue index Kliniken Schmieder (FKS) for detecting motor fatigue in patients with MS using kinematic gait analysis. The FKS relies on the chaos theoretical term "attractor", which, if unchanged, is a necessary and sufficient indicator of a stable dynamical system. We measured the acceleration of the feet at the beginning of and shortly before stopping a treadmill walking task in 20 healthy subjects and 40 patients with multiple sclerosis. The attractor and movement variability were calculated. In the absence of muscular exhaustion a significant difference in the attractor and movement variability between the two time points demonstrates altered motor control indicating fatigue. Subjects were classified using the FKS. All healthy subjects had normal FKS and thus no fatigue. 29 patients with MS were classified into a fatigue group and 11 patients into a non-fatigue group. This classification agreed with the physician’s observation and video analyses in up to 97 % of cases. The FKS did not correlate significantly with the overall and motor dimensions of the fatigue questionnaire scores in patients with MS and motor fatigue. The common concept of fatigue as overall subjective sensation of exhaustion can be affected by conditions including depression, sleep disorder and others. FKS constitutes a robust and objective measure of changes in motor performance. Therefore, the FKS allows correct identification of motor fatigue even in cases where common comorbidities mask motor fatigue.

Fachgebiet (DDC)

610 Medizin

Schlagwörter

Gait analysis, Fatigue index, Physical performance, Lactate level, Heart rate

Zitieren

ISO 690

SEHLE, Aida, Manfred VIETEN, Simon SAILER, Annegret MÜNDERMANN, Christian DETTMERS, 2014. Objective assessment of motor fatigue in multiple sclerosis : the Fatigue index Kliniken Schmieder (FKS). In: Journal of Neurology. 2014, 261(9), pp. 1752-1762. ISSN 0340-5354. eISSN 1432-1459. Available under: doi: 10.1007/s00415-014-7415-7

BibTex

@article{Sehle2014-09Objec-28415,
  year={2014},
  doi={10.1007/s00415-014-7415-7},
  title={Objective assessment of motor fatigue in multiple sclerosis : the Fatigue index Kliniken Schmieder (FKS)},
  number={9},
  volume={261},
  issn={0340-5354},
  journal={Journal of Neurology},
  pages={1752--1762},
  author={Sehle, Aida and Vieten, Manfred and Sailer, Simon and Mündermann, Annegret and Dettmers, Christian}
}

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Universitätsbibliographie

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