Regulatory gene networks that shape the development of adaptive phenotypic plasticity in a cichlid fish

Schneider, Ralf F.; Li, Yuanhao; Meyer, Axel; Gunter, Helen M.

Regulatory gene networks that shape the development of adaptive phenotypic plasticity in a cichlid fish

Dateien

Schneider_284875.pdfGröße: 1.25 MBDownloads: 994

Datum

2014

Open Access-Veröffentlichung

Open Access Green

Sammlungen

Biologie
Zukunftskolleg

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

Molecular Ecology. 2014, 23(18), pp. 4511-4526. ISSN 0962-1083. eISSN 1365-294X. Available under: doi: 10.1111/mec.12851

Zusammenfassung

Phenotypic plasticity is the ability of organisms with a given genotype to develop different phenotypes according to environmental stimuli, resulting in individuals that are better adapted to local conditions. In spite of their ecological importance, the developmental regulatory networks underlying plastic phenotypes often remain uncharacterized. We examined the regulatory basis of diet-induced plasticity in the lower pharyngeal jaw (LPJ) of the cichlid fish Astatoreochromis alluaudi, a model species in the study of adaptive plasticity. Through raising juvenile A. alluaudi on either a hard or soft diet (hard shelled or pulverized snails) for between one and eight months, we gained insight into the temporal regulation of 19 previously identified candidate genes during the early stages of plasticity development. Plasticity in LPJ morphology was first detected between three and five months of diet treatment. The candidate genes, belonging to various functional categories, displayed dynamic expression patterns that consistently preceded the onset of morphological divergence and putatively contribute to the initiation of the plastic phenotypes. Within functional categories we observed striking co-expression, and transcription factor binding site analysis was used to examine the prospective basis of their co-regulation. We propose a regulatory network of LPJ plasticity in cichlids, presenting evidence for regulatory cross-talk between bone and muscle tissues, which putatively facilitates the development of this highly integrated trait. Through incorporating a developmental time-course into a phenotypic plasticity study, we have identified an interconnected, environmentally responsive regulatory network that shapes the development of plasticity in a key innovation of East African cichlids.

Fachgebiet (DDC)

570 Biowissenschaften, Biologie

Schlagwörter

Evo-devo, developmental time-course, bone remodeling, pharyngeal jaw, cichlid, Astatoreochromis alluaudi

Zitieren

ISO 690

SCHNEIDER, Ralf F., Yuanhao LI, Axel MEYER, Helen M. GUNTER, 2014. Regulatory gene networks that shape the development of adaptive phenotypic plasticity in a cichlid fish. In: Molecular Ecology. 2014, 23(18), pp. 4511-4526. ISSN 0962-1083. eISSN 1365-294X. Available under: doi: 10.1111/mec.12851

BibTex

@article{Schneider2014-09Regul-28487,
  year={2014},
  doi={10.1111/mec.12851},
  title={Regulatory gene networks that shape the development of adaptive phenotypic plasticity in a cichlid fish},
  number={18},
  volume={23},
  issn={0962-1083},
  journal={Molecular Ecology},
  pages={4511--4526},
  author={Schneider, Ralf F. and Li, Yuanhao and Meyer, Axel and Gunter, Helen M.}
}

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