A Useful Application of Benzyl Trichloroacetimidate for the Benzylation of Alcohols

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1993
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Eckenberg, Peter
Richter, Norbert
Schmeck, Carsten
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Tetrahedron. 1993, 49(8), pp. 1619-1624. ISSN 0040-4020. eISSN 1464-5416
Zusammenfassung

Primary, secondary and tertiary alcohols, which are sensitive under basic or acidic reaction conditions, can be 0-benxylated under mild acidic reaction conditions using benxyl 2,2,2-trichloroacetimidate as the benxylation agent. Chiral substrates, which have a tendency towards racemixation under basic reaction conditions, can be benxylated without any loss of chirality.

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ISO 690ECKENBERG, Peter, Ulrich GROTH, Thomas HUHN, Norbert RICHTER, Carsten SCHMECK, 1993. A Useful Application of Benzyl Trichloroacetimidate for the Benzylation of Alcohols. In: Tetrahedron. 1993, 49(8), pp. 1619-1624. ISSN 0040-4020. eISSN 1464-5416
BibTex
@article{Eckenberg1993Usefu-10008,
  year={1993},
  title={A Useful Application of Benzyl Trichloroacetimidate for the Benzylation of Alcohols},
  number={8},
  volume={49},
  issn={0040-4020},
  journal={Tetrahedron},
  pages={1619--1624},
  author={Eckenberg, Peter and Groth, Ulrich and Huhn, Thomas and Richter, Norbert and Schmeck, Carsten}
}
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