Universität zu Köln

Ultsch, Bernhard, Koester, Ingrid, Reinhold, Thomas ORCID: 0000-0001-5169-7029, Siedler, Anette, Krause, Gerard ORCID: 0000-0003-3328-8808, Icks, Andrea, Schubert, Ingrid and Wichmann, Ole ORCID: 0000-0003-2353-7188 (2013). Epidemiology and cost of herpes zoster and postherpetic neuralgia in Germany. Eur. J. Health Econ., 14 (6). S. 1015 - 1027. NEW YORK: SPRINGER. ISSN 1618-7601

Full text not available from this repository.

Abstract

After acquiring a varicella virus infection, the virus can reactivate and cause herpes zoster (HZ)-a painful skin rash. A complication of HZ is long-term persistence of pain after the rash has resolved (so-called postherpetic neuralgia, PHN). We aimed to describe the epidemiology of HZ/PHN and to estimate HZ/PHN-related costs in the German statutory health insurance (SHI) system (similar to 85 % of the total population). Treatment data of one large SHI was utilized, containing data on approximately 240,000 insured and their utilisation of services in 2004-2009. Identification of HZ- and PHN-cases was performed based on 'International Statistical Classification of Diseases' and specific medications using a control-group design. Incidences per 1,000 person-years (PY) and cost-of-illness for 1 year following HZ-onset considering the payer and societal perspective were calculated. All amounts were inflated to 2010 Euros. Population-figures were standardised and extrapolated to the total SHI-population in Germany in 2010. A mean annual incidence of 5.79 HZ-cases per 1,000 PY was observed, translating into an estimated 403,625 HZ-cases per year in the total SHI-population. Approximately 5 % of HZ-cases developed PHN. One HZ-case caused on average a,not sign210 and a,not sign376 of costs from the payer and societal perspective, respectively. The development of PHN generated additional costs of a,not sign1,123 (a,not sign1,645 societal perspective). Total annual HZ/PHN-related costs were estimated at a,not sign182 million (a,not sign105 million) to society (payer). HZ and PHN place a considerable burden on the German SHI-system. Since HZ-vaccines will soon be available, a health-economic evaluation of these vaccines should be conducted.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Ultsch, Bernhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Koester, Ingrid UNSPECIFIED UNSPECIFIED UNSPECIFIED Reinhold, Thomas UNSPECIFIED orcid.org/0000-0001-5169-7029 UNSPECIFIED Siedler, Anette UNSPECIFIED UNSPECIFIED UNSPECIFIED Krause, Gerard UNSPECIFIED orcid.org/0000-0003-3328-8808 UNSPECIFIED Icks, Andrea UNSPECIFIED UNSPECIFIED UNSPECIFIED Schubert, Ingrid UNSPECIFIED UNSPECIFIED UNSPECIFIED Wichmann, Ole UNSPECIFIED orcid.org/0000-0003-2353-7188 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-471685
DOI:	10.1007/s10198-012-0452-1
Journal or Publication Title:	Eur. J. Health Econ.
Volume:	14
Number:	6
Page Range:	S. 1015 - 1027
Date:	2013
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1618-7601
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language HEALTH ECONOMIC-EVALUATION; VARICELLA VACCINATION; UNITED-STATES; OLDER-ADULTS; BURDEN; POPULATION; DISEASE; INSURANCE; SHINGLES; DATABASE Multiple languages Economics; Health Policy & Services Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/47168