Universität zu Köln

Niehoff, Julius Henning, Woeltjen, Matthias Michael, Laukamp, Kai Roman, Borggrefe, Jan ORCID: 0000-0003-2908-7560 and Kroeger, Jan Robert (2021). Virtual Non-Contrast versus True Non-Contrast Computed Tomography: Initial Experiences with a Photon Counting Scanner Approved for Clinical Use. Diagnostics, 11 (12). BASEL: MDPI. ISSN 2075-4418

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Abstract

The present study evaluates the diagnostic reliability of virtual non-contrast (VNC) images acquired with the first photon counting CT scanner that is approved for clinical use by comparing quantitative image properties of VNC and true non-contrast (TNC) images. Seventy-two patients were retrospectively enrolled in this study. VNC images reconstructed from the arterial (VNCa) and the portalvenous (VNCv) phase were compared to TNC images. In addition, consistency between VNCa and VNCv images was evaluated. Regions of interest (ROI) were drawn in the following areas: liver, spleen, kidney, aorta, muscle, fat and bone. Comparison of VNCa and VNCv images revealed a mean offset of less than 4 HU in all tissues. The greatest difference between TNC and VNC images was found in spongious bone (VNCv 86.13 HU +/- 28.44, p < 0.001). Excluding measurements in spongious bone, differences between TNC and VNCv of 10 HU or less were found in 40% (VNCa 36%) and differences of 15 HU or less were found in 72% (VNCa 68%) of all measurements. The underlying algorithm for the subtraction of iodine works in principle but requires adjustments. Until then, special caution should be exercised when using VNC images in routine clinical practice.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Niehoff, Julius Henning UNSPECIFIED UNSPECIFIED UNSPECIFIED Woeltjen, Matthias Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Laukamp, Kai Roman UNSPECIFIED UNSPECIFIED UNSPECIFIED Borggrefe, Jan UNSPECIFIED orcid.org/0000-0003-2908-7560 UNSPECIFIED Kroeger, Jan Robert UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-570071
DOI:	10.3390/diagnostics11122377
Journal or Publication Title:	Diagnostics
Volume:	11
Number:	12
Date:	2021
Publisher:	MDPI
Place of Publication:	BASEL
ISSN:	2075-4418
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language QUANTITATIVE ACCURACY; CT; IMAGES; PERFORMANCE; IODINE Multiple languages Medicine, General & Internal Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/57007